Chromatin Architecture
The three-dimensional organisation of DNA, histones and regulatory complexes that helps control genome activity inside the nucleus.
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Immunometabolism
The reciprocal control between cellular metabolic pathways and the activation, differentiation and function of immune cells.
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Spatial Transcriptomics
Methods that measure gene expression while preserving the locations and neighbourhoods of cells within tissue.
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Circadian Rhythms
Endogenous biological cycles near twenty-four hours that coordinate physiology and behaviour with environmental time.
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Gene Regulatory Networks
Interacting genes, regulatory DNA and molecular factors that control when and where biological programmes are expressed.
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Epigenetic Regulation
Heritable or persistent control of gene activity mediated by chromatin state without changing DNA sequence.
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Single-Cell RNA Sequencing
Methods that measure transcript abundance in individual cells to resolve heterogeneous biological populations.
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CRISPR-Cas9 Gene Editing
A programmable molecular system that can cut DNA near a sequence selected by a guide RNA.
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