CAR T-Cell Therapy
Cell therapy in which a patient's or donor's T cells are engineered with a synthetic receptor that recognises a selected disease antigen.
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Immunometabolism
The reciprocal control between cellular metabolic pathways and the activation, differentiation and function of immune cells.
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Autophagy
Cellular pathways that deliver cytoplasmic material to lysosomes or vacuoles for degradation, quality control and recycling.
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Circadian Rhythms
Endogenous biological cycles near twenty-four hours that coordinate physiology and behaviour with environmental time.
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Gene Regulatory Networks
Interacting genes, regulatory DNA and molecular factors that control when and where biological programmes are expressed.
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Organoids
Three-dimensional, self-organising cell cultures that reproduce selected structural and functional features of organs.
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Computational Protein Design
The algorithmic creation of amino-acid sequences expected to fold into structures with specified biochemical functions.
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Synthetic Biology
The design and construction of biological systems using engineering principles, quantitative models and molecular tools.
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Mitochondrial ATP Synthesis
How electron transport and a proton gradient power ATP production across the inner mitochondrial membrane.
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Photosynthesis
The biological conversion of light energy into chemical energy, coupled to carbon fixation in plants, algae and some bacteria.
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