Liquid Biopsy
Analysis of tumour-derived DNA, cells, vesicles or other biomarkers in blood and body fluids to characterise cancer non-invasively.
SCIENDIA Knowledge Desk
Read article
Collaborative knowledge
Sciendia Wiki
A living academic reference written, refined and transparently versioned by the Sciendia community.
14published pages
Sign in to contribute
Collaborative knowledgeSearch
14 results
Wiki pages are public to read. Every signed-in member can create and improve them.
Clear search
Microbial Synthetic Communities
Designed groups of microbial species used to study and engineer ecological interactions with controlled membership and function.
SCIENDIA Knowledge Desk
Read article
Chromatin Architecture
The three-dimensional organisation of DNA, histones and regulatory complexes that helps control genome activity inside the nucleus.
SCIENDIA Knowledge Desk
Read article
Protein Language Models
Machine-learning models that learn statistical representations of amino-acid sequences for prediction and molecular design.
SCIENDIA Knowledge Desk
Read article
Spatial Transcriptomics
Methods that measure gene expression while preserving the locations and neighbourhoods of cells within tissue.
SCIENDIA Knowledge Desk
Read article
Viral Evolution
The change of viral populations through mutation, selection, recombination, migration and genetic drift across hosts and time.
SCIENDIA Knowledge Desk
Read article
Cancer Immunotherapy
Treatments that redirect, strengthen or release immune responses to recognise and control malignant cells.
SCIENDIA Knowledge Desk
Read article
Organoids
Three-dimensional, self-organising cell cultures that reproduce selected structural and functional features of organs.
SCIENDIA Knowledge Desk
Read article
Synthetic Biology
The design and construction of biological systems using engineering principles, quantitative models and molecular tools.
SCIENDIA Knowledge Desk
Read article
Microbiome Metagenomics
The culture-independent analysis of collective microbial genomes recovered from an environmental or host-associated sample.
SCIENDIA Knowledge Desk
Read article
Epigenetic Regulation
Heritable or persistent control of gene activity mediated by chromatin state without changing DNA sequence.
SCIENDIA Knowledge Desk
Read article
Single-Cell RNA Sequencing
Methods that measure transcript abundance in individual cells to resolve heterogeneous biological populations.
SCIENDIA Knowledge Desk
Read article
Antibiotic Resistance
The inherited ability of microorganisms to survive or grow at drug concentrations that would normally inhibit them.
SCIENDIA Knowledge Desk
Read article
CRISPR-Cas9 Gene Editing
A programmable molecular system that can cut DNA near a sequence selected by a guide RNA.
SCIENDIA Knowledge Desk
Read article