CAR T-Cell Therapy
Cell therapy in which a patient's or donor's T cells are engineered with a synthetic receptor that recognises a selected disease antigen.
SCIENDIA Knowledge Desk
Read article
Collaborative knowledge
Sciendia Wiki
A living academic reference written, refined and transparently versioned by the Sciendia community.
16published pages
Sign in to contribute
Collaborative knowledgeSearch
16 results
Wiki pages are public to read. Every signed-in member can create and improve them.
Clear search
Liquid Biopsy
Analysis of tumour-derived DNA, cells, vesicles or other biomarkers in blood and body fluids to characterise cancer non-invasively.
SCIENDIA Knowledge Desk
Read article
Immunometabolism
The reciprocal control between cellular metabolic pathways and the activation, differentiation and function of immune cells.
SCIENDIA Knowledge Desk
Read article
Microfluidics
The control of very small fluid volumes in engineered channels for analysis, synthesis and biological experimentation.
SCIENDIA Knowledge Desk
Read article
mRNA Therapeutics
Medicines that deliver engineered messenger RNA so cells transiently produce a therapeutic protein or antigen.
SCIENDIA Knowledge Desk
Read article
Bioprinting
Layer-by-layer fabrication of living tissue constructs using cells, biomaterials and spatially controlled deposition.
SCIENDIA Knowledge Desk
Read article
Spatial Transcriptomics
Methods that measure gene expression while preserving the locations and neighbourhoods of cells within tissue.
SCIENDIA Knowledge Desk
Read article
Circadian Rhythms
Endogenous biological cycles near twenty-four hours that coordinate physiology and behaviour with environmental time.
SCIENDIA Knowledge Desk
Read article
Cancer Immunotherapy
Treatments that redirect, strengthen or release immune responses to recognise and control malignant cells.
SCIENDIA Knowledge Desk
Read article
Organoids
Three-dimensional, self-organising cell cultures that reproduce selected structural and functional features of organs.
SCIENDIA Knowledge Desk
Read article
Causal Inference
Statistical and experimental frameworks for estimating how interventions change outcomes rather than merely describing associations.
SCIENDIA Knowledge Desk
Read article
Epigenetic Regulation
Heritable or persistent control of gene activity mediated by chromatin state without changing DNA sequence.
SCIENDIA Knowledge Desk
Read article
Single-Cell RNA Sequencing
Methods that measure transcript abundance in individual cells to resolve heterogeneous biological populations.
SCIENDIA Knowledge Desk
Read article
Messenger RNA Vaccines
Vaccines that deliver temporary genetic instructions so cells produce an antigen and train adaptive immunity.
SCIENDIA Knowledge Desk
Read article
Antibiotic Resistance
The inherited ability of microorganisms to survive or grow at drug concentrations that would normally inhibit them.
SCIENDIA Knowledge Desk
Read article
CRISPR-Cas9 Gene Editing
A programmable molecular system that can cut DNA near a sequence selected by a guide RNA.
SCIENDIA Knowledge Desk
Read article